Which is the derivative of adamantane?

Memantine: An NMDA Antagonist Without the Undesirable Side Effects. Memantine is an adamantane derivative similar to amantadine, a drug with antiviral and antiparkinsonian properties (Chen et al., 1992).

How many types of H are in adamantane?

16 hydrogen
The adamantane molecule is composed of only carbon and hydrogen and has Td symmetry. Therefore, its 16 hydrogen and 10 carbon atoms can be described by only two sites, which are labeled in the figure as 1 (4 equivalent sites) and 2 (6 equivalent sites).

Is adamantane poisonous?

Adamantanes, formally designated tricyclo[3.3. Not all adamantane derivatives are extremely toxic, and many synthetic derivatives such as amantadine are used clinically (Figure 1) [3]. Amantadine is used as an antiviral agent [3], and as a muscle relaxant in the treatment of Parkinson’s disease [4].

What is adamantane used for?

Adamantanes are a class of antiviral medications which are active against influenza A but not influenza B viruses. A medication used to treat dyskinesia in Parkinson’s patients receiving levodopa, as well as extrapyramidal side effects of medications.

What is the point group of adamantane?

tetrahedral point
Adamantane is a small hydrocarbon molecule with pure sp3 hybridized carbon atoms arranged in a tetrahedral point group, often referred to as a diamondoid.

Who discovered adamantane?

Adamantane (formally tricyclo[3.3. 1.13,7]decane) is an exquisitely symmetrical hydrocarbon that was originally isolated from petroleum in 1933 by the Czech researchers S. Landa and V. Machacek.

What is c10h160?

Camphor | C10H16O – PubChem.

What is the name of the compound C10H16?

Cyclodecyne
Cyclodecyne | C10H16 – PubChem.

How do you make norbornene?

Norbornene is made by a Diels–Alder reaction of cyclopentadiene and ethylene. Many substituted norbornenes can be prepared similarly. Related bicyclic compounds are norbornadiene, which has the same carbon skeleton but with two double bonds, and norbornane which is prepared by hydrogenation of norbornene.

What is the name of C10H16?

What is the melting point of Isoborneol?

DL-Isoborneol Properties Melting point: 212-214 °C (subl.)(

What is CIO chemistry?

ChEBI. Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−.

What is the yield of adamantane synthesis?

The adamantane synthesis yield was later increased to 60% and 98% by ultrasound and super acid catalysts. Today, adamantane is an affordable chemical compound with a cost of about $1 a gram. All the above methods yield adamantane as a polycrystalline powder.

How do you convert adamantane to 1-bromadamantane?

Boiling of adamantane with bromine results in a monosubstituted adamantane, 1-bromadamantane. Multiple substitution with bromine is achieved by adding a Lewis acid catalyst. The rate of bromination is accelerated upon addition of Lewis acids and is unchanged by irradiation or addition of free radicals.

What is the natural source of adamantane?

Petroleum remains the only natural source of adamantane; the content varies from between 0.0001% and 0.03% depending on the oil field and is too low for commercial production. Beside adamantane, petroleum contains more than thirty of its derivatives.

How many equivalent sites are there in adamantane?

The adamantane molecule is composed of only carbon and hydrogen and has high T d symmetry. Therefore, its 16 hydrogen and 10 carbon atoms can be described by only two sites, which are labeled in the figure as 1 (4 equivalent sites) and 2 (6 equivalent sites).